Spams and Spam Cops

I've cranked my spam filter up to block everything not whitelisted, and I've set up an account on Spamcop. I've submitted a few dozen spam reports using a temporary mail account to see what would happen. What has happened is the spammers are still winning. I had 48 unwanted messages between Friday night and Monday morning. (Two were actually opt-in mailing list announcements; as I find those I've been either whitelisting them, or unsubscribing). Not good. What else can be done? I hear that even newly created e-mail accounts with completely un-publicized addresses start getting spam!